Vaccination is very effective in preventing severe cases of Covid-19, even against the Delta variant, a large study in France has shown.
Research published Monday, which focuses on preventing severe Covid and death, not infections, looked at 22 million people over the age of 50 and found that those who had received jabs were 90 percent less likely to be hospitalized or die.
The results confirm observations from the US, UK and Israel, but the researchers say it is the largest study of its kind so far.
Looking at data collected from December 2020, when France launched its jab campaign, the researchers compared the results of 11 million vaccinated people with 11 million unvaccinated subjects.
They formed pairs that paired an unvaccinated individual with a vaccinated counterpart from the same region and of the same age and sex, tracing them from the date of the vaccinated person’s second puncture to July 20.
Starting 14 days after a second dose, vaccinated subjects’ risk of severe Covid was reduced by 90 percent, according to research by Epi-Phare, an independent drug safety research group working closely. collaboration with the French government.
Vaccination appears to be almost as effective against the Delta variant, with 84 percent protection for people 75 and older and 92 percent for people 50 to 75 years old.
However, that estimate is only based on one month of data, as the variant became dominant in France only in June.
“The study should be followed up to include the results from August and September,” epidemiologist Mahmoud Zureik, director of Epi-Phare, told AFP.
The study covers vaccination with the Pfizer / BioNtech, Moderna and AstraZeneca jabs, but not Jannsen, which was licensed much later and used much less in France.
The results also suggest that during the study period, up to five months, vaccination protection against severe Covid did not decrease.